Work out the safe sodium correction rate and the infusion rate needed to raise serum sodium without exceeding the daily limit that risks osmotic demyelination.
仅为教学估算,临床必须个体化治疗。
| Item | Formula / Note | Source / Standard |
|---|---|---|
| Correction ceiling | sodium should rise no more than eight to ten millimoles per litre per day | Adrogue & Madias 2000, N Engl J Med |
| Osmotic demyelination | rapid correction risks osmotic demyelination especially in chronic hyponatraemia | Adrogue & Madias 2000, N Engl J Med |
| Monitoring interval | sodium is rechecked every four to six hours to adjust the rate | Adrogue & Madias 2000, N Engl J Med |