Estimate creatinine clearance with the Cockcroft-Gault equation from age, weight, sex and serum creatinine, then normalise it to 1.73 m² using the body surface area derived from the entered height; the estimate still used for many renal drug dose adjustments.
用于药物剂量调整。
| Item | Formula / Note | Source / Standard |
|---|---|---|
| Equation origin | creatinine clearance uses age weight and creatinine with a sex correction | Cockcroft & Gault 1976, Nephron |
| Difference from filtration | the equation estimates clearance not filtration and they converge when function is normal | KDIGO 2012, CKD evaluation |
| Drug dosing | label dose adjustments often rely on this equation and are not interchangeable | WHO Model Formulary |