Input DFI and HDS percentages to assess sperm DNA integrity and its clinical significance in male fertility evaluation.
| Item | Formula | Source-Standard |
|---|---|---|
| Index definition | DFI = denatured sperm / total sperm examined x 100% | Evenson DP et al. Hum Reprod 1999;14:1039-1049 (SCSA) |
| Risk strata | DFI below 15% is low risk, 15-30% moderate and above 30% high risk | Evenson DP et al. Hum Reprod 1999;14:1039-1049 (SCSA) |
| Clinical advice | Elevated DFI prompts evaluation for varicocele, infection and lifestyle factors | Agarwal A et al. World J Mens Health 2020;38:e40 |
精子 DNA 碎片指数(DFI)反映精子 DNA 损伤程度,HDS 反映染色质成熟度。两者常用于男性不育、复发性流产及辅助生殖预后评估。
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